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Psychosocial IntegrityThiamine deficiency · confabulation · irreversible

Wernicke-Korsakoff SyndromeNCLEX cheat sheet

Thiamine deficiency · confabulation · irreversible

0 key facts 5 practice questions Reviewed Oct 2026
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The Two Phases

  • Wernicke — confusion, ataxia, nystagmus. May reverse.
  • Korsakoff — memory loss with confabulation. Does NOT reverse.

Confabulation

  • Memory gaps filled with invented stories
  • The client is not lying — they believe it
  • Redirect. Never present reality.

Treatment

  • Thiamine (vitamin B1) replacement
  • Thiamine BEFORE glucose — always
  • Correct magnesium too
  • Stops it worsening; does not undo damage
Key takeaway

Thiamine deficiency · confabulation · irreversible

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A client in acute alcohol withdrawal is prescribed which medication class to prevent seizures and DTs?

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